ANTIGENIC PROMOTION

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Antigenic Promotion

Rabbits were immunized with p-azobenzene arsonic acid derivatives of human serum albumin (HA-As) or of dissociated keyhole limpet hemocyanin. The IgM response to the hapten was evaluated in terms of the number of hapten-specific plaque-forming cells in the lymph node draining the injection site. In some experiments, antibody was measured by agglutination of tanned and sensitized erythrocytes. T...

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Expression and Antigenic Evaluation of VacA Antigenic Fragment of Helicobacter Pylori

Objective(s): Helicobacter pylori, a human specific gastric pathogen is a causative agent of chronic active gastritis. The vacuolating cytotoxin (VacA) is an effective virulence factor involved in gastric injury. The aim of this study was to construct a recombinant protein containing antigenic region of VacA gene and determine its antigenicity.   Materials and Methods: The antigenic region of V...

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expression and antigenic evaluation of vaca antigenic fragment of helicobacter pylori

objective(s): helicobacter pylori, a human specific gastric pathogen is a causative agent of chronic active gastritis. the vacuolating cytotoxin (vaca) is an effective virulence factor involved in gastric injury. the aim of this study was to construct a recombinant protein containing antigenic region of vaca gene and determine its antigenicity.   materials and methods: the antigenic region of v...

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Antigenic variance.

Antigenic variance may be defined as phenotypic expressions that are due to slight differences in gene sequences coding for viral proteins with antigenic reactivity (CALISHER 1988). Evidence for antigenic variance due to mutations and reassortment in the Bunyaviridae family is great and has been obtained by several different approaches. The main intent of this review, however, is not to discuss...

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Antigenic Modulation

Antigenic modulation (the loss of TL antigens from TL+ cells exposed to TL antibody in the absence of lytic complement) has been demonstrated in vitro. An ascites leukemia, phenotype TL.1,2,3, which modulates rapidly and completely when incubated with TL antiserum in vitro, was selected for further study of the phenomenon. Over a wide range of TL antibody concentrations modulation at 37 degrees...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1971

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.134.3.693